Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_35c0eae40381d1da7d9701f0c85bffee |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00659 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00722 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00549 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00711 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6869 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6837 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6834 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6837 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6869 |
filingDate |
2021-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2e7d60c4c12d53d28952608acb5a0fd0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5d67e42e481e7cceed531038d4bd5dfa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_341276ec4c66a1c27b0e3d3c7398e70f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4ec8431a073ea956624505768253c52d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8483f4d78ae9ebe74d2b82e867c5c40c |
publicationDate |
2022-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2022228201-A1 |
titleOfInvention |
Molecular arrays and methods for generating and using the arrays |
abstract |
Provided in some aspects are methods for light-controlled in situ surface patterning of a substrate. Compositions such as nucleic acid arrays produced by the methods are also disclosed. In some embodiments, provided herein is photocontrollable hybridization, where oligonucleotides with photo-caged bases prevent hybridization of complementary nucleic acid strands. Uncaging of the oligonucleotides allows hybridization and/or ligation of nucleic acid molecules at the exposed area. A large diversity of barcodes can be created in molecules on the substrate via sequential rounds of light exposure, hybridization, and ligation. |
priorityDate |
2020-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |