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filingDate 2019-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9a185fa4eb8d90349b06f6e096fdcaa0
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publicationDate 2022-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2022221459-A1
titleOfInvention A method of predicting response to treatment in cancer patients
abstract A method of predicting response to chemotherapy in a patient with cancer is described. The method comprises the steps of incubating an ADCC-capable molecule, an immune response modulator, a cancer cell line that expresses a target of the ADCC-capable molecule, and a sample of the patient's blood, for a period of time, determining an ADCC response of the cancer cell line, comparing the ADCC response with a reference ADCC response, and predicting the patient's response to chemotherapy based on the comparison. In one aspect, the cancer is a HER2+ cancer, the ADCC-capable molecule is an antibody targeting HER2, and the cancer cell lines is a HER2+ cancer cell line.
priorityDate 2018-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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