| abstract |
The present disclosure relates to extracellular vesicles, e.g., exosomes, comprising a cytokine, e.g., Interleukin-12 (IL-12), and, optionally, a TB antigen. Also provided herein are methods of inducing an immune response against Mycobacterium tuberculosis in a subject in need thereof comprising administering an extracellular vesicle comprising a cytokine, e.g., IL-12, and, optionally, a TB antigen. |