http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2022218710-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a819eda0adf22936a52362eeebb9fb4 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 |
| filingDate | 2020-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_648d2b393267f87ff98966e4ee9cc885 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e343433afc62b0839a678e08ad4d9c09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9fba4c6401b9ec0236a129374d86ad5f |
| publicationDate | 2022-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2022218710-A1 |
| titleOfInvention | Inhibition of Neddylation for Treatment of MS |
| abstract | The use of neddylation inhibitors to treat immune related conditions is described. Dysregulated immune and inflammatory responses underlie a number of conditions, including multiple sclerosis. Neddylation is involved in processes underlying the activation, activity, and proliferation of immune cells that drive these conditions, including CD4+ T cells. Inhibition of neddylation thus provides a target for intervention to prevent and treat such conditions. Inhibition of E1 NEDD8 activating enzymes, such as NAE may be utilized in treatment, for example by pevonedistat or other NAE inhibitors. |
| priorityDate | 2019-05-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 322.