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filingDate 2021-10-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2022-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2022218645-A1
titleOfInvention Application of Trans-1,3-Dilinolein in the Preparation of Medicaments for Treating Gastric Cancer, Stomachic Tonic, Health Products and Foods
abstract Some embodiments of the disclosure provide new uses of trans-1,3-dilinolein as medicaments and food. In an embodiment, an application of trans-1,3-dilinolein in the preparation of stomachic tonic and an application thereof include the preparation of medicaments for treating gastric cancer. Cell experiments show that trans-1,3-dilinolein promotes the proliferation of human gastric mucosal epithelial cell line GES-1 under normal oxygen and hypoxic conditions and it has concentration-dependent killing effect on human gastric cancer cell line HGC-27 and killing effect on hypoxic gastric cancer cells. At a concentration of 300 μm and more, trans-1,3-dilinolein kills gastric cancer cells significantly and the killing effect becomes more significant under hypoxic conditions.
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