abstract |
Provided herein are aqueous antibody formulations that exhibit improved stability and low viscosity. The formulations include an antibody or an antigen-binding fragment, a buffer, and a salt selected from the group of magnesium glutamate, magnesium acetate, magnesium aspartate, magnesium sulfate, arginine acetate, arginine aspartate, arginine glutamate, arginine sulfate, lysine acetate, lysine aspartate, lysine glutamate, lysine sulfate, sodium acetate, sodium aspartate, sodium glutamate, sodium sulfate, lithium acetate, lithium aspartate, lithium glutamate, or lithium sulfate, where the formulations have a pH of about 4 to about 8 and, optionally an osmolality of about 250 mOsm/kg to about 1500 mOsm/kg |