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filingDate 2020-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2022-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2022218274-A1
titleOfInvention Methods for Estimating Key Phenotypic Traits for Obstructive Sleep Apnea and Simplified Clinical Tools to Direct Targeted Therapy
abstract A method of predicting the likelihood of responding to one or more obstructive sleep apnea (OSA) treatments for obstructive sleep apnea (OSA) of a candidate subject, the method including the steps of: (a) measuring a first series of polysomnography and anthropometric parameters for at least a collection of OSA sufferers; (b) correlating the parameters with at least one of the corresponding upper-airway collapsibility (Pcrit), arousal threshold, loop gain and pharyngeal muscle responsiveness measurement of each subject; (c) determining a corresponding description structure describing the correlation of step (d); and (d) utilising the corresponding description structure, in conjunction with a series of polysomnography and anthropometric parameters measured for the candidate subject to predict the likelihood of responding to one or more obstructive sleep apnea (OSA) treatments to thereby provide a clinical decision diagnostic tool for obstructive sleep apnea.
priorityDate 2019-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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