http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2022212192-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a864329f69db5da3ce856121f76fe371 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-0887 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2400-0655 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2400-0638 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2200-0673 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2015-1006 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2400-0487 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L3-502784 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N15-1468 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L3-502738 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01L3-00 |
| filingDate | 2020-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_34492b55de2c6712b972574bd8f7a2b6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_81e6b88c9e0c862a8b890fb08ae7438e |
| publicationDate | 2022-07-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2022212192-A1 |
| titleOfInvention | Microfluidic Device for High-Throughput Screening of Tumor Cell Adhesion and Motility |
| abstract | Microfluidic devices and methods are provided for high-throughput generation, culturing, and analysis of cell spheroids, with subsequent isolation of selected cell spheroids for further analysis or isolation and expansion of cells from the spheroids. Any desired types of cells and matrices can be combined to form the cell spheroids and used to screen drugs and immunotherapy agents or methods, including in a personalized medicine format. Cell spheroids also can be cultivated and analyzed under hypoxic conditions. A particular advantage of the technology is the ability to isolate, enrich, and/or expand cells identified as having, or induced to have, desirable properties, such as immune cells that can be produced ex vivo and returned to the patient to combat a tumor or pathogen in vivo. |
| priorityDate | 2019-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 28.