http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2022211984-A1

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filingDate 2021-01-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_da6b1a308e685e4cbef1609af4a78b18
publicationDate 2022-07-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2022211984-A1
titleOfInvention Device to Reduce and Redirect Leaks
abstract The device which may be attached inside or outside the pancreas/abdomen during surgery addresses leaks of pancreatic juice or pancreatic effluent (PE) after resection by redirecting and inactivating PE. Specifically the PE enzymes (proteases) are inactivated. Redirection is through an internal biodegradable self powered self eliminating drain with increasing gradient and then targeting or inactivating the effluent with active pharmaceutical ingredients (API) such as-protease inhibitors which are contained in graduated micro-encapsulated particles (GMEPs) coated with pH and time release shells which the device locates at optimum locations in the pancreas/abdomen. Another iteration is redirecting PE by containing the device within a mesh filled with GMEP comprising protease inhibitors (antiprotease) to inactivate PE before flowing out via openings in the mesh into the abdominal cavity as an inactivated innocuous fluid.
priorityDate 2021-01-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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