| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e5d629a660feee6cc9edb49960df3f5d |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-0819
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2400-086
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2200-0663
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2400-0487
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2200-12 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M23-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M35-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M33-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L3-502707
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L3-502746
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L3-502761 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01L3-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M3-06 |
| filingDate |
2021-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_687dadb6fcb0093aa103e81bd555ed33
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_070816e0a778285303658a150accb80c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_314baec786b546cf6b8f45e36d829a8d |
| publicationDate |
2022-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2022204902-A1 |
| titleOfInvention |
High-throughput microfluidic chip having parallelized constrictions for perturbing cell membranes |
| abstract |
A microfluidic chip for causing the delivery of a payload to a cell comprises a plurality of constrictions configured to allow a cell suspension to flow through one or more of the plurality of constrictions from a first fluid flow region to a second fluid flow region within the microfluidic chip, wherein a cross-sectional width of each of the plurality of constrictions is less than a diameter of cells in the cell suspension, such that membranes of the cells are perturbed when passing through the constrictions such that a payload is able to pass through the perturbed cell membranes, and wherein a quotient of a cross-sectional area over a cross-sectional perimeter of each of the plurality of constrictions is greater than greater than or equal to 0.5 μm. |
| priorityDate |
2020-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |