http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2022202809-A1

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filingDate 2021-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_491d9c2ee1b0516229d9dcf662bcb653
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_161500836c1ce5ccb512da2384140bb5
publicationDate 2022-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2022202809-A1
titleOfInvention Methods of treating depression with vortioxetine
abstract The present disclosure relates to methods of transitioning patients or obese patients being treated with vortioxetine to treatment with a monoamine oxidase inhibitor (MAOI). The methods provided include delaying administration of the MAOI for certain time periods after stopping administration of vortioxetine. The patients or obese patients possess various capabilities of metabolizing vortioxetine. The current disclosure also includes methods of switching patients to a MAOI intended to treat psychiatric disorders while being treated with vortioxetine. The methods disclosed further comprise determining vortioxetine plasma clearance and washout time for patients with different body fat status and/or different CYP2D6 metabolizer status.
priorityDate 2017-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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