| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cc64a0225ee1b588c1d7af77250eee01
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_06a4b4c0ff06bf9c7b97fa9b26ce5d12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_09fc02a407043ca0a10e2dbe5fcb6159 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-541
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-496
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-16 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 |
| filingDate |
2020-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fe4500d76fe609991a8860172acb3add
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9046ea8a52f109e0d535d8fbb209e5ab
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d36eb566272ee694aef12de47a11d98a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b6e001b16175a557865215cb15b5a886 |
| publicationDate |
2022-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2022194937-A1 |
| titleOfInvention |
Protein kinase inhibitors and uses thereof for the treatment of diseases and conditions |
| abstract |
Identified compounds demonstrate protein kinase inhibitory activity. More specifically, the compounds are demonstrated to inhibit receptor interacting kinase 2 (RIPK2) and/or Activin-like kinase 2 (ALK2) and/or receptor interacting kinase 3 (RIPK3). Compounds that are either dual RIPK2/ALK2 inhibitors or that preferentially inhibit RIPK2 or ALK2 or RIPK3 could provide therapeutic benefit. Compounds that function as RIPK3 inhibitors provide therapeutic benefit in the treatment of inflammatory and degenerative conditions. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2022064163-A1 |
| priorityDate |
2019-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |