http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2022187311-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f8c0982b0f02b1ed6d20a315370a3a3a |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-70503 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-324 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-70589 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-745 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6887 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
filingDate | 2021-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_395a8852af760ebc992a81940a64937e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7401d41ef758957e24528908eb6aafa4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1efeb04b5477290197b2ebef670a249a |
publicationDate | 2022-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-2022187311-A1 |
titleOfInvention | Methods for the detection and quantification of circulating endothelial cells |
abstract | The disclosure provides methods for detecting circular endothelial cells (CECs) in a non-enriched blood sample. The present disclosure is based, in part, on the unexpected discovery that CECs can be detected in non-enriched blood samples. The present disclosure is further based, in part, on the discovery that CECs can be detected in non-enriched blood samples by combining the detection of one or more immunofluorescent markers in the nucleated cells of a non-enriched blood sample with an assessment of the morphology of the nucleated cells. The present disclosure is further based, in part, on the discovery that CECs can be detected in non-enriched blood samples by comparing the immunofluorescent marker staining and morphological characteristics of CECs with the immunofluorescent marker staining and morphological characteristics of WBCs. The methods disclosed herein serve to classify human subject in myocardial infarction (MI) patients or healthy controls. |
priorityDate | 2013-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 288.