Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_158e30bcf4126d7cc40cfb0ea3f79797 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_36389cdf579846a37f770c664b61f7ca http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7a92f3f18bbf82939c2f7a7192cc2d1c http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ca34176dadec1ad805cdb39cb9139e5a |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-65 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-65 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P27-02 |
filingDate |
2020-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_352fdc3b75f5c151c757b263176cd1c7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ca7cb646de81f8a7b43657f517fcdd69 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d36850e3d7500499ce819512e7aed669 |
publicationDate |
2022-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2022184102-A1 |
titleOfInvention |
Compositions and methods for treating age-related macular degeneration |
abstract |
Provided are chemically modified tetracycline (CMT) derivatives for the treatment of non-exudative macular degeneration. The CMT derivatives lack antimicrobial activity, include a phenol ring, and a chemical structure sufficient to chelate Zn2+. Methods of inhibiting and/or minimizing inflammation in a subject, including administering to the subject a dose of a CMT derivative, are also provided. Methods of treating non-exudative age-related macular degeneration (AMD) are provided. |
priorityDate |
2019-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |