abstract |
The present invention relates to composition of sleep aid transdermal patch comprising natural herbal ingredient as active ingredient, synergistic additives and pharmaceutically acceptable excipients. The present invention relates to composition of transdermal patch comprising valerian as natural herbal ingredient, skullcap, licorice, passionflower as synergistic additives and pharmaceutically acceptable excipients to aid sleep in insomnia conditions. The present invention also relates to an efficient process for the preparation of sleep aid transdermal patch by using hot-melt coating technique (HMC), comprising the steps of melting, mixing, coating, laminating and cutting. |