| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_82cbc291d77c061ac9a216f86ec010a3 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6886 |
| filingDate |
2019-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ae22ee9b73d0ea69b3914ce9730e6148
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3e75dfeeefbd201f762f7d72c08faf2f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d347ba2d123eff67a4eea12fa0d85d74
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_81e7f16c15d7210442f06d29ec16b83f |
| publicationDate |
2022-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2022170106-A1 |
| titleOfInvention |
Novel marker of epithelial-mesenchymal transition in pancreatic cancer |
| abstract |
In order to elucidate the mechanism of malignant alteration of pancreatic cancer caused by BACH1, changes in the gene expression depending on the expression level of BACH1 in the pancreatic cancer cell line were clarified by RNA sequencing. As a result of experiments on in vitro migration ability and invasion ability and in vivo orthotopic transplantation, BACH1 was found to be used as an excellent biomarker for epithelial-to-mesenchymal transition of pancreatic cancer when used alone or in combination with its downstream regulator FOXA1. |
| priorityDate |
2019-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |