http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2022145366-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_04f657a8261a2fc879c089c99e63eb0b |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-686 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6851 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-689 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-689 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-686 |
| filingDate | 2021-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e49d93c236dab440378ba8b704c571c7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e1bad7ce99ef8cff04a283836eec1681 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_56227c1fef705243d1bc9ab8f216023f |
| publicationDate | 2022-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2022145366-A1 |
| titleOfInvention | Early detection of drug-resistant mycobacterium tuberculosis |
| abstract | The present invention relates to oligonucleotides, methods, and kits useful for detecting an antibiotic-resistant subpopulation within a heteroresistant population of Mycobacterium tuberculosis in a sample. An amplicon of a target locus is obtained from the sample. The target locus comprises a region of interest which comprises one or more minor variants associated with the antibiotic resistance. The target locus is selected from the group consisting of: pncA, tlyA, gidB, rpsL, gyrB, embB, ahpC promoter, rplC, and combinations thereof. The amplicon is sequenced on a Next Generation Sequencing (NGS) platform. The region of interest is interrogated to detect the one or more minor variants and thus, the antibiotic-resistant subpopulation of Mycobacterium tuberculosis. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-116024360-A |
| priorityDate | 2020-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 209.