| abstract |
The present invention provides an α-synuclein aggregate binding agent that has high binding selectivity for an α-synuclein aggregate. n The α-synuclein aggregate binding agent contains a compound represented by a formula (I), a pharmaceutically acceptable salt thereof, or a solvate thereof: n n n n n n n n n n in the formula (I), R 1 and R 2 are each independently selected from the group consisting of hydrogen, alkyl, alkenyl, acyl, and hydroxyalkyl; R 3 is hydrogen or halogen; the ring A is a benzene or pyridine ring; the ring B is represented by the following formula (i) or (ii): n n n n n n n n n n R 4 and R 5 are each independently selected from the group consisting of hydrogen, hydroxy, alkoxy, haloalkoxy, halohydroxyalkoxy, and aminoalkyl. |