Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c564804e4e89ea0871bbeefd81569950 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-4353 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5085 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5047 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P33-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-365 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-365 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P33-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7048 |
filingDate |
2020-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e876a32d3a0ce4cd2ecc468340e01851 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9f20ed29ff973afacee2a4751f3a4644 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7092d343f0df07c9b3786fa43c04d3f5 |
publicationDate |
2022-05-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2022133688-A1 |
titleOfInvention |
Macrocyclic lactone anthelmintics against nematodes |
abstract |
The present invention relates to a milbemycin for use in control, treatment and/or prevention of infections with nematodes, preferably filariae, more preferably Dirofilaria immitis which are resistant to at least one other macrocyclic lactone anthelmintic. The present invention further relates to the use of milbemycins for stimulating attachment of polymorphonuclear neutrophils (PMNs) and/or peripheral blood mononuclear cells (PBMCs) to larvae of nematodes, as well as to a method for stimulating attachment of PMNs and/or PBMCs to larvae of nematodes. In a further aspect, the present invention relates to an in vitro assay for determining and/or characterizing an agent for control, treatment and/or prevention of an infection with nematodes. |
priorityDate |
2019-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |