http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2022133630-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d0274e2de0fa1bce13bb26712a10b923 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1694 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1682 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1647 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-107 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-26 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-107 |
filingDate | 2022-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d23610a1e2bd501a863c7aba6212b7ba http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_36245b4d7de6a472985688bcc21ddc2f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_840a8c960b40024e4d05bb1ad6db18d2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2d6c1249fba71848179c01aca7ea0c3d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_473aca2b8ea88d1d2affba8305e065c2 |
publicationDate | 2022-05-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-2022133630-A1 |
titleOfInvention | Preparation method of sustained-release microparticles |
abstract | The whole preparation process of the sustained-release microparticles is at normal or low temperature, which is highly advantageous for the preparation of a polymer-based composition from a high-temperature-sensitive drug, particularly a protein, nucleic acid and peptide drug, and the bioactivity of the active substance can be maintained to the greatest extent throughout the process compared to the disclosed technology; at the same time, the prepared sustained-release microparticles have an excellent sustained-release effect close to zero order, and the drug concentration is stabilized during the release, which overcomes the defects that the microparticles obtained by the conventional S/O/W process of pre-preparing the drug microparticles have no drug release in the earlier stage and a rapid release of the drug in the later stage; and in addition, the sustained-release microparticles have higher drug loading rate and drug encapsulation rate. |
priorityDate | 2018-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 740.