Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bb0a16607be22143b8138c6be3abcb14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_916075766043ce900399a4c2eee9f054 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a819eda0adf22936a52362eeebb9fb4 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y302-01014 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-2442 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-42 |
filingDate |
2021-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b0934eee04b192d03ee73626a457478d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bec4907d0a09e4d3c324dd15edfd9e3a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_060152ff96916145867f672d690e1c90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1684231df674a8c5a9fefa47c8f12ddb |
publicationDate |
2022-04-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2022119790-A1 |
titleOfInvention |
Mutant Chitinase With Enhanced Expression and Activity |
abstract |
Provided are engineered novel forms of the acidic mammalian chitinase having enhanced expression and having improved catalytic activity. The novel forms of the mammalian acidic chitinase comprise one or more amino acid substitutions, relative to the native sequence, that impart these improved properties. The novel proteins may be used therapeutically for the prevention and treatment of airway conditions associated with environmental chitin exposure and accumulation. |
priorityDate |
2020-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |