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filingDate 2020-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2022-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2022105041-A1
titleOfInvention Method for manufacturing a solid administration form and solid administration
abstract For manufacturing a solid administration form comprising at least one active pharmaceutical ingredient, a flowable but setting composite material comprising the at least one active pharmaceutical ingredient is added together and set to generate the solid administration form. The flowable composite material is liquefied and delivered to a discharge unit. Small portions of liquefied composite material are intermittently discharged through an outlet into a setting unit. The flowable composite material comprises a polymer and at least one active pharmaceutical ingredient dispersed or dissolved within the polymer. The small portions are droplets and the solid administration form is generated by adding droplets that stick together before or during the setting of the liquefied composite material. An average diameter of the droplets can be less than 350 μm. There can be a void space between at least some small portions, resulting in a porous structure of the solid administration form.
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