| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fefabf67e9090550c512fea1d64d4812 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C59-52 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C67-343
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C51-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C51-42 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-42 |
| filingDate |
2021-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0579f872483a0ca1d846da9fa950d1f6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fa37bf0734cee0914021aae4738c2f3c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b22d8fb76398c4256ef9dcc2d95330ac
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_290203b60b28f3931d031293c9f3cf03
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_744262c24c7cbbb14aa4b93db965acce
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf3841f0c515e127c71de37fac02cf74 |
| publicationDate |
2022-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2022098139-A1 |
| titleOfInvention |
Method for synthesizing artepillin c and intermediate compound thereof |
| abstract |
The present invention relates to a method for synthesizing artepillin C and a synthetic method for synthesizing an intermediate compound for use in preparing artepillin C. The structural formula of artepillin C is shown in the following formula (IV), and the intermediate compound is shown in the following formula (II). The synthesis method includes the following steps: a first reaction step: in the presence of a base initiator, a compound A shown in formula I and 3,3-dimethylallyl bromide are mixed, the reaction continues for a first reaction time and is stopped to generate an intermediate of artepillin C shown in formula II; and a second reaction step: the intermediate of artepillin C is dissolved in an aqueous alcohol solution and then mixed with an alkali metal salt, and the reaction continues for a second reaction time to generate artepillin C. |
| priorityDate |
2020-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |