Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_751562df05f1831baef905641425c407 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y40-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y30-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0085 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0002 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-143 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-145 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-146 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-1887 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0085 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0093 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0009 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0054 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0021 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 |
filingDate |
2019-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8503b44eb99d8d3de4257d9e10986bd4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d598b874e61bb2726aafab87543c4e7f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1069baa4c27733fa348147510658e474 |
publicationDate |
2022-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2022096665-A1 |
titleOfInvention |
Bimodal nanoparticle conjugates for non-invasive central nervous system tissue imaging |
abstract |
Ligand-bimodal nanoparticle conjugates capable of crossing the blood-brain barrier are disclosed. Methods of making and using the conjugates also are disclosed. The bimodal nanoparticle includes a polymeric matrix, one or more magnetic particles disposed within the polymeric matrix or conjugated to an outer surface of the polymeric matrix, and a dye disposed within the polymeric matrix. A ligand for a blood-brain barrier amino acid transporter is conjugated to the outer surface of the bimodal nanoparticle. |
priorityDate |
2018-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |