http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2022093211-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4bd24d0edc441a277cf5d128b2c97b31 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B30-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B30-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B40-20 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B30-10 |
filingDate | 2021-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a8fa03a4fecf7acf060cee3c8b3c662d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b4cd1e00b313def6f8bb212cff587c94 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2c79905167fe6be8b35e6123769155fb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b65f8af896dc9cbee6f9d9e2d5750f31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6ad0cb84139a4a40559a5d37e9e77782 |
publicationDate | 2022-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-2022093211-A1 |
titleOfInvention | Detecting cross-contamination in sequencing data |
abstract | Detecting cross-contamination between test samples used for determining cancer in a subject is beneficial. To detect cross-contamination, test sequences including at least one single nucleotide polymorphism are prepared using genome sequencing techniques. Some of the test sequences can be filtered to improve accuracy and precision. A prior contamination probability for each test sequence is determined based on a minor allele frequency. A contamination model including a likelihood test is applied to a test sequence. The likelihood test obtains a current contamination probability representing the likelihood that the test sample is contaminated. The contamination model can also determine a likelihood that the sample includes loss of heterozygosity representing the likelihood that the test sequence is contaminated. Test samples that are contaminated are removed. A source for the contaminated test sample can be found by comparing contaminated test sequences to other test sequences. |
priorityDate | 2020-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 168.