http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2022089547-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b46bb1a0dd448dde7550917be389c71c |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0048 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P27-02 |
| filingDate | 2019-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1a1d294d8ce70feef3eaa63422d577f5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_42487bfdebecab6bc8a2db6bf3e2a8a8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_96868205357808a95a8aa19e2457c18e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_73e2fe1d15efe7d7d5f8e2d9d0380e5f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_78ce96101619b6af98a6d78b060ef1a6 |
| publicationDate | 2022-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2022089547-A1 |
| titleOfInvention | Compounds for use as therapeutically active substances in the treatment and/or prevention of neuroretinal diseases |
| abstract | A compound of the formula (I) n n n n n n n n n n or a pharmaceutically acceptable salt thereof, wherein: A is a 5-oxazolyl residue or a pyridine-4-yl residue, R 1 is selected from fluoro and chloro; R 2 , R 3 , R 4 , R 5 and R 6 of the phenyl ring B are independently from each other selected from hydrogen, a linear or branched alkyl having 1 to 4 carbon atoms, trifluoromethyl, 2,2,2-trifluoroethyl, methylsulfanyl, ethylsulfanyl, methylsulfonyl, ethylsulfonyl, difluoromethoxy, trifluoromethoxy, fluoro, bromo, chloro, methoxy, ethoxy, propoxy, butoxy, hydroxy and amino; and at least two of R 2 , R 3 , R 4 , R 5 and R 6 are hydrogens, with the proviso that if R 1 is chloro, R 5 is not methoxy. Said compounds are useful as therapeutically active substances in the treatment and/or prevention of neuroretinal diseases, and in particular in the treatment and/or prevention of neuroretinal diseases leading to photoreceptor loss or degeneration of the outer retina. |
| priorityDate | 2007-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 335.