http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2022088266-A1

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filingDate 2021-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aed5da36b0e6462b02638cc9588bf895
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publicationDate 2022-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2022088266-A1
titleOfInvention Blood Coagulation-Promoting Silk Fibroin-Polypeptide Electrospun Membrane and Preparation Method Thereof
abstract The present invention discloses a blood coagulation-promoting silk fibroin-polypeptide electrospun membrane and a preparation method thereof. The electrospun membrane is made by using silkworm silk fibroin as a carrier and adding the polypeptide GPRPPSEHLQIT. It is mainly used for promoting blood coagulation, and is a blood coagulation material that can targetedly bind to human fibrinogen. The preparation method includes the steps of dissolving, filtering, dialyzing, concentrating and freeze-drying silkworm cocoons after degumming to obtain silk fibroin freeze-dried powder. The polypeptide used in the present invention is a polypeptide obtained by self-screening. Compared with other polypeptides, it can specifically targetedly bind to human fibrinogen.
priorityDate 2019-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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