Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1893e58a79a78de604ff4b09e05c578b |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y402-01001 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-54 |
filingDate |
2020-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7cf4656319b557dc1a71693b06e91dec http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_416016f9bd52ebff83c62e87fbf65b4c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9bda16e5d1b603b9bccf75ed53e16d1d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c25065800fd097c2206756f438b4eb2f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0baf42013a63092234356e305aa01b0a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2693c67c1de7ac6b44c1eedd61356160 |
publicationDate |
2022-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2022088118-A1 |
titleOfInvention |
Bicyclic peptide ligands specific for caix |
abstract |
The present invention relates to polypeptides which are covalently bound to non-aromatic molecular scaffolds such that two or more peptide loops are subtended between attachment points to the scaffold. In particular, the invention describes peptides which are high affinity binders of carbonic anhydrase IX (CAIX). The invention also includes drug conjugates comprising said peptides, conjugated to one or more effector and/or functional groups, to pharmaceutical compositions comprising said peptide ligands and drug conjugates and to the use of said peptide ligands and drug conjugates in preventing, suppressing or treating a disease or disorder mediated by CAIX. |
priorityDate |
2019-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |