Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8db2889ce927060a670f07b97e9cc8d0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0c4322cb4de342be2dbedcbe0c278f6f |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N2005-0661 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N2005-1098 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-0066 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N5-062 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-37 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61N5-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-37 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K41-00 |
filingDate |
2021-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_34078661db02741c67dfcf6768e78e78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5b6aea3c1e8ccb5e3d56782bcfb8ad7b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ea3f34b67c7799b26c01bddef4fbc26d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_073ffa49d76ac739716ff5686850aad6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a7a99df4206c9727eed599fed8836d50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bcc18b122ec50d0e998a58478304ae8e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_db70c658389d169ab93a2ba5c5ce4ad6 |
publicationDate |
2022-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2022080045-A1 |
titleOfInvention |
Phosphor-containing drug activator, suspension thereof, system containing the suspension, and methods for use |
abstract |
A method for treating a disease in a subject in need thereof is provided involving infusing 8-methoxypsoralen (8-MOP) and a phosphor-containing drug activator into a diseased site in the subject; and delivering a dose of x-rays to the subject for production of the ultraviolet and visible light inside the subject to activate the photoactivatable drug and induce a persistent therapeutic response, the dose including a pulsed sequence of x-rays delivering from 0.5-2 Gy to the tumor, wherein the phosphor-containing drug activator includes an admixture of two or more phosphors capable of emitting ultraviolet and visible light upon interaction with x-rays; the two or more phosphors including Zn2SiO4:Mn2+ and (3Ca3(PO4)2Ca(F, Cl)2: Sb3+, Mn2+) at a ratio (Zn2SiO4:Mn2+):(3Ca3(PO4)2Ca(F, Cl)2: Sb3+, Mn2+)) of from 1:10 to 10:1; wherein each of the two or more phosphors have at least one coating selected from an ethyl cellulose coating or a diamond-like carbon coating. |
priorityDate |
2016-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |