abstract |
A compound of formula (Ib′) or anyone of its metabolites or a pharmaceutically acceptable salt thereof for use for treating and/or preventing cancer and/or dysplasia n n n n n n n n n n wherein R is independently hydrogen, halogen, —CN, hydroxyl, (C 1 -C 3 )fluoroalkyl, (C 1 -C 3 )fluoroalkoxy, (C 3 -C 6 )cycloalkyl, —NO 2 , —NR 1 R 2 , (C 1 -C 4 )alkoxy, phenoxy, —NR 1 —SO 2 —NR 1 R 2 , —NR 1 —SO 2 —R 1 , —NR 1 —C(═O)—R 1 , —NR 1 —C(═O)—NR 1 R 2 , —SO 2 —NR 1 R 2 , —SO 3 H, —O— SO 2 —OR 3 , —O—P(═O)(OR 3 )(OR 4 ), —O—CH 2 —COOR 3 , (C 1 -C 3 )alkyl, said alkyl being optionally mono- or di-substituted by a hydroxyl group, a -A-(CH 2 ) m —B—NRaRb group, or a —(O—CH 2 —CH 2 ) p —O—Ra group. The present disclosure also relates to a compound of formula (IVb′) or a pharmaceutically acceptable salt thereof for use for treating and/or preventing cancer and/or dysplasia. |