Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_69b4de7d64ebafc368b849bca94eab18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5b08ee9911b210281171b3be84640a13 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6869 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-7051 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-907 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-725 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6869 |
filingDate |
2018-10-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9de774e61cc78f1b7a849b5f43136e80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a6d27640bf0efa62c9b98c5e5cbc488e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3fa31d2d51a2c4011bbd673663db398e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_13d8ce24b58f0f651470ce6a03ed4cfa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0c6a12c0f8835fdcb8254c9884e8a055 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_62c4ff8426085547039a8f1de738d357 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b55ab371586b83269977655fa3a5c103 |
publicationDate |
2022-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2022064253-A1 |
titleOfInvention |
TECHNIQUE FOR CREATING ANTIGEN-SPECIFIC REGULATORY T CELLS (Treg) IN WHICH EFFECTOR T CELL (Teff) ANTIGEN RECEPTORS ARE USED |
abstract |
The present disclosure provides a technique for producing regulatory T cells specific to a desired antigen. Regulatory T cells specific to an antigen are produced by a method that includes: a step for identifying a T cell receptor (TCR) clone present in an effector T cell population specific to an antigen in an effector T cell donor; and a step for introducing all or part of the nucleic acid sequence of the TCRα gene and all or part of the nucleic acid sequence of the TCRβ gene included in the clone into a regulatory T cell, said step comprising introducing the TCRα and the TCRβ so as to be expressed in pairs. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2020368279-A1 |
priorityDate |
2017-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |