Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f61b04ae22fadbf6221bfc44fcb84c43 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d33087dfb06f23a561b692aecc073feb |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-0075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-417 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1866 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-417 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
filingDate |
2020-01-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1a22a460a97ae1ecfda37bb3a1dce6bc |
publicationDate |
2022-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2022062439-A1 |
titleOfInvention |
Localized administration of rna molecules for therapy |
abstract |
The present invention relates to local delivery to an organ and/or tissue of an agent such as a peptide and/or polypeptide, by administration of an RNA molecule encoding such agent to an afferent blood vessel of the organ and/or tissue. The agent is thus able to provide its biological function, e.g., therapeutic effect, locally and avoid unwanted systemic effects, including any toxicity observed when the agent encoded by the RNA and/or the encoding RNA itself is administered systemically. |
priorityDate |
2019-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |