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filingDate 2021-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5efc7a7b635f94dae5de368632ac27ff
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publicationDate 2022-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2022048977-A1
titleOfInvention Polymeric forms of h-nox proteins
abstract The invention provides polymeric H-NOX proteins for the delivery of oxygen with longer circulation half-lives compared to monomeric H-NOX proteins. Polymeric H-NOX proteins extravasate into and preferentially accumulate in tumor tissue for sustained delivery of oxygen. The invention also provides the use of H-NOX proteins as radiosensitizers for the treatment of brain cancers.
priorityDate 2013-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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Total number of triples: 582.