http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2022040315-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9e86e89035f5a19cbec3257b6b1fa6cb |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-595 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-14 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-14 |
filingDate | 2021-07-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5c3d91b17b9d5a56f173c95f66eea3fa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d5a41c09797e52c25d826c7663ef6045 |
publicationDate | 2022-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-2022040315-A1 |
titleOfInvention | Nuclease-dendrimer formulations for covid-19 and broad-spectrum antiviral therapy and prophylaxis |
abstract | Compositions of nucleases in formulations with dendrimers are used in pharmaceutically effective dosages as therapeutics for covid-19 and a broad spectrum of viruses in various embodiments. When cationized nucleases are mixed and/or complexed with a dendrimer, an unexpected positive dendrimer effect is manifest. This positive dendrimer effect is shown to be highly effective for catalyzing anti-viral RNase properties. In various embodiments compositions of cationized nucleases in combination with a dendrimer demonstrated this synergistic amplification of anti-viral effectiveness and are used in pharmaceutically effective dosages as therapeutics against covid-19 and a broad spectrum of viruses. An exemplar formulation which exhibits a positive dendrimer effect is cationized RNase A mixed and/or complexed with gen 2 PAMAM dendrimer. |
priorityDate | 2020-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1678.