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filingDate 2019-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6fd992070d80b69a8490cf7d88750cea
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publicationDate 2022-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2022033266-A1
titleOfInvention Copper ion-doped carbon dots, preparation method and application thereof as photosensitizer for photodynamic therapy
abstract Copper ion-doped carbon dots (Cu-CDs) and a preparation method thereof are disclosed. The preparation method includes the following steps: using copper nitrate as a dopant to generate a complex of polyacrylic acid and copper ions as a precursor by an in situ polymerization; standing overnight, and performing repeated suction filtration to collect filter residues; then, performing pyrolysis and carbonization to generate carbonized products, dispersing in ultrapure water, taking a supernatant, and then performing extraction and purification to obtain the CDs. When the Cu-CDs prepared by the present invention are used in photodynamic therapy, photothermal/photodynamic synergistic therapy is not required, and the Cu-CDs are suitable for the therapeutic process of skin cancer, lung cancer, pancreatic cancer, esophageal cancer, brain glioma, as well as some skin diseases and ophthalmological diseases.
priorityDate 2019-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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