| abstract |
Disclosed are compounds of the formulas (I), (II), and (II): which are A 1 adenosine receptor agonists, pharmaceutical compositions comprising such compounds, and a method of use of these compounds, wherein Y, R 1 -R 6 , R 10 -R 15 , and R 20 -R 22 are as defined in the specification. These compounds are selective to the A 1 adenosine receptor, and are contemplated for use in the treatment or prevention of a number of diseases or conditions, for example, for inducing and/or maintaining a hypothermic and/or hypometabolic state for treatment of a mammal. |