http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2022018799-A1

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filingDate 2019-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2022-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2022018799-A1
titleOfInvention System and methods for measuring analyte concentration
abstract A multiplex aptamer sensor platform for determining the concentration of a target analyte in sample. Aptamers are modified with redox-active molecule and selected to exhibit conformational change in the presence of target analyte, so that faradic discharge can be sampled at the electrode surface. Faradic discharge is converted to digital signal for calculation of the analyte concentration. The platform is attached to a test cartridge utilizing a vertical connection to a reader device. Sensor electrodes are manufactured using PCB techniques yet the platform is both accurate and commercially usable. No mixing, microfluidics or calibration are required.
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