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publicationDate 2022-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2022018782-A1
titleOfInvention Methods for determining viral titre using raman spectroscopy
abstract The use of Raman spectroscopy for the monitoring and assessment of viral titre is disclosed. A method of quantifying viral titre in a sample using Raman spectroscopy, comprises the steps of: (a) providing a sample and irradiating the sample with a light source; (b) measuring the total intensity of Raman scattered light within each one of a plurality of wavenumber ranges to obtain a wavenumber intensity data set for the sample, wherein the plurality of wavenumber ranges are pre-selected and are characteristic of the vims in the sample; (c) performing mathematical data processing steps on the wavenumber intensity data; and (d) quantifying the viral titre based upon the output of the mathematical data processing steps.
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