| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_92372bcefb0073dd236f752c73f2eed2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_54d112629ffe022ebab46c4bee61f80a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0dfc1e831fea5c10d030a89b10ba9a08 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-14 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate |
2019-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d01674d3b6fb70eeddd10f514366e68f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_27b1bcd422d8d6fc37beee572983b972
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1d45cd147dd44788de00fa6d93bfb212
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_010be56d36b07cd62dc6dbe69f724779
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_11811a297db0ee53bf030ae9197077cb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fc3bda1ec2329f9c360e88df9b162922
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_773beeb4220e657cdb3c3c359676a53e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_540dc63d19c459dcf388feeb365a2b67 |
| publicationDate |
2022-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2022017529-A1 |
| titleOfInvention |
Novel l-proline sulfonamide derivatives comprising pyrazolo[4,3- e]tetrazolo[4,5-b][1,2,4]triazine system, method of manufacturing thereof, uses thereof and pharmaceutical composition comprising the same |
| abstract |
The subject matter of the invention relates to novel sulfonamide derivatives of 7-methyl-5-phenyl-pyrazolo[4,3-c]tetrazolo[4,5-b] [1,2,4]triazine comprising L-proline or 4-hydroxy-L-proline in the sulfonamide group. The novel compounds exhibit cytostatic activity against gastric cancer cell (AGS) and colorectal cancer cell (DLD-1 and HT-29) lines and may be used as novel medicaments which have anticancer action. The subject matter of the invention also relates to a method of manufacturing such derivatives, as well as uses thereof and a pharmaceutical composition comprising the same. |
| priorityDate |
2018-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |