| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9fb7bbc09927d64558e1e99a3b7c719b |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2400-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-414 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3886
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3813
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3804
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-24 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-24 |
| filingDate |
2019-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f7c13aba618a06728569ebd161ec812e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a4e25f8c2393942847df9f41bea8fa50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b52e543cf16f7eabff1762385ba8400b |
| publicationDate |
2022-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2022016321-A1 |
| titleOfInvention |
Dermal substitutes and engineered skin with rete ridges |
| abstract |
Disclosed herein are dermal substitutes comprising: fibroblasts positioned in a biologically compatible matrix, the biologically compatible matrix comprising a plurality of protrusions on at least one surface; wherein the plurality of protrusions comprise a length and width sufficient to improve a dermal graft outcome. Also disclosed are methods of treating a skin wound on a subject, the method comprising: contacting a skin wound with a herein disclosed dermal substitute. Also disclosed are methods of preparing a dermal graft for transplantation, the method comprising: culturing fibroblasts positioned in a biologically compatible matrix in a scaffold comprising a plurality of protrusions on at least one surface; wherein the scaffold comprises a plurality of protrusions comprising a length and width sufficient to improve a dermal graft outcome. |
| priorityDate |
2018-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |