| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5137d258248f7d51a126917b4cd77e97 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y204-02019
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y104-03016
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y205-01072 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y104-03016
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1077
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y204-02019
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0022
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1048
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y205-01072
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1085 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-20 |
| filingDate |
2019-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a5d8decf72ca1946f80442dd14275121
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b991a7c98ec8886396de012e483a5ab3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c1fd71b2a032ba1555108cac6ac72a51
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_60d4c6529c3c196a1af27a3c703bdcea |
| publicationDate |
2022-01-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2022010266-A1 |
| titleOfInvention |
Microbial hosts engineered for increased tolerance to temperature shifts |
| abstract |
The present invention relates to microbial host cells that have been engineered for increased tolerance to temperature shifts, for increased performance at temperatures different from the microorganism's optimal temperature and/or for changing at least one of the microorganism's cardinal temperatures by replacing an endogenous NAD + biosynthesis gene by a heterologous gene encoding a corresponding enzyme with another temperature profile and/or from a microorganism with a different optimum growth temperature. The invention further relates to processes wherein the engineered microbial host cells are used for producing a fermentation product, and to the use nucleotide sequences encoding NAD + biosynthesis gene for changing at least one of a microorganism's cardinal temperatures and/or for improving a microorganism's tolerance to temperature shifts. |
| priorityDate |
2018-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |