| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_07c9542186133097bd6bbb7d92393090 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57407
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-6615
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K33-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-685
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-69
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57484 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K33-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-6615
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-69
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-685 |
| filingDate |
2021-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_647ff55483a518c5c8cb5f4a903d87e4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7cdec8ffd103b55ab4421792a5b83893
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fccf559d9905a9a8486af24cc4effa45
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2965e67cf5fc1b052835e8032f4bedf3 |
| publicationDate |
2022-01-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2022008442-A1 |
| titleOfInvention |
Phospholipid Ether Analogs for Imaging and Targeted Treatment of Pediatric Solid Tumors |
| abstract |
It is disclosed herein that that certain alkylphosphocholine analogs are preferentially taken up by malignant pediatric tumor cells. The alkylphophocholine analogs are compounds having the formula: n n n n n n n n n n or salts thereof, wherein n is an integer from 12 to 24; and R 2 is —N + (CH 3 ) 3 . The compounds can be used to treat pediatric solid tumors or to detect pediatric solid tumors. In therapeutic treatment, R 1 includes a radioactive iodine isotope that locally delivers therapeutic dosages of radiation to the malignant pediatric tumor cells that preferentially take up the compound. In detection/imaging applications, R 1 includes a detection moiety, such as a fluorophore or a radioactive iodine isotope. |
| priorityDate |
2016-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |