Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3edb9aa141cda1fdc8cb548d0c57f59c |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M2037-0046 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J2333-14 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-7023 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1635 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0021 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1732 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-605 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J3-075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y101-03004 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08F220-387 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-443 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-08 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J3-075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 |
filingDate |
2019-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_397eb25db5a96c8535149ebe66118e0b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba4199c55eecebac93c85158bf4e5081 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d258cb0122469f49e7e272de7e478c2e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_173676a5ba6fb41f778a090f450f7a94 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ceebe0c81b4595dc2c5e0218a862f70b |
publicationDate |
2021-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2021393543-A1 |
titleOfInvention |
Composition and device for preventing hypoglycemia and use thereof |
abstract |
A composition for preventing or treating hypoglycemia in a patient in need thereof has a microgel that includes crosslinked polymers containing glucose-responsive moieties; and blood glucose-raising therapeutic agent loaded on or within the microgel. The microgel further includes any one or a combination of a stabilizing component and a loading-assisting component for the blood glucose- raising therapeutic agent. The polymers containing the glucose-responsive moieties form secondary crosslinks in response to low glucose level, thereby causing shrinking of the microgel and rapid release of the blood glucose-raising therapeutic agent. The composition can be used to prepare a composite microneedle patch for preventing or treating hypoglycemia, where the composition is embedded or integrated within an array of the microneedles of the microneedle patch device. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115746196-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114272374-A |
priorityDate |
2018-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |