abstract |
Compounds of formula I are provided: n n n n n n n n n n wherein X is NH, or CH 2 , Y is a single bond, or —CHR 5 —, R 1 is H, C 1 -C 4 alkyl, or C 1 -C 4 hydroxyalkyl, R 2 and R 2 ′ are each independently H, C 1 -C 4 alkyl, or C 1 -C 4 hydroxyalkyl, each R 3 is independently H, halo, —CF 3 , C 1 -C 4 alkyl, or C 1 -C 4 alkoxy, C 3 perhaloalkyl, each R 4 is independently H, halo, or C 1 -C 4 alkyl, R 5 is C 1 -C 4 alkoxy, r is integer from 0 to 3; and p is integer from 0 to 3. |