| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d452ebbe234b18c80d0462dc24578da3 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M35-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M41-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M23-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M25-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M25-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M23-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M23-26 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-12 |
| filingDate |
2019-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e156bf1a9ab455b7077271faedf97f79 |
| publicationDate |
2021-11-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2021348103-A1 |
| titleOfInvention |
Mesh rolled scaffold and advanced bioreactor |
| abstract |
The present invention provides mesh rolled scaffold devices and bioreactor systems that can provide a large surface-to-volume ratio for expanded cell culture. The mesh rolled scaffolds minimize shear stress on cultured cells and support sufficient and uniform mass transfer rates of gases and nutrients. The mesh rolled scaffolds can be connected to a media source via holders in bioreactor systems to support large-scale expansion and maintenance of cell cultures. The present invention also provides the bioreactor systems that can include dialyzers and heat exchangers to modify media and other fluids passing through the systems. The bioreactor systems include media and other fluid reservoirs that can support high stirring rates between about 100 and 10000 rpm, and the overall systems can be pressurized between about 1 and 10 atm to increase gas exchange rates. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2022401973-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11752509-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11752510-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023152488-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023118872-A1 |
| priorityDate |
2018-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |