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filingDate 2021-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7adb94693cd39466119ae60d195b950e
publicationDate 2021-11-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2021346437-A1
titleOfInvention Novel treatment of dysphagia
abstract This disclosure provides methods for treating dysphagia in a patient in need of esophageal dilation of his/her esophageal stricture. The methods according to this disclosure comprise:i. injecting circumferentially into the esophageal stricture area a sterile pharmaceutical composition comprising a pharmaceutically acceptable fluid carrier and tissue matrix allograft particles composed of human amnion and chorion membranes, wherein the amnion membrane is de-epithelized; andii. performing pneumatic dilation of the esophageal stricture with a balloon dilator.The methods of this disclosure are particularly suitable for treating a complex and scarred cervical esophageal stricture, including reoccurring cervical esophageal strictures. The present methods may be particularly beneficial for cancer patients, including head and neck cancer patients, who were previously treated with external beam radiation and/or chemotherapy and/or a surgery for his/her cancer.
priorityDate 2020-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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