abstract |
The present invention relates to a lipid vesicle carrying a nucleic acid molecule for use as a medicament, wherein the lipid vesicle has a hydrodynamic diameter Dh of less than 300 nm. The lipid vesicle is for oral administration, and the nucleic acid molecule is delivered to one or more of the target tissues selected from the group consisting of the central nervous system, spleen, gastrointestinal tract, liver and T-cells. |