Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ad8d9a4ab24376d00e7a01957bdcf20b |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2565-607 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2565-525 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2525-107 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2563-131 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6816 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54393 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54373 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6804 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6804 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-543 |
filingDate |
2021-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4ead6fe397158f424a830167df0f3369 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_35613407c09aedc5252b6a89d45c6d32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9bad4dedd70c6ec0fa9ea54c35b6a7fa |
publicationDate |
2021-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2021341473-A1 |
titleOfInvention |
Molecular wires for detecting a biological or chemical entity or event |
abstract |
Enantiomeric pairs of molecular wires comprised of oligomeric nucleic acids, wherein the oligomers of each wire possess identical nucleobase pair sequences and thus identical conductivity as between wires, are constructed and used to sense biological or chemical entities of interest at the cellular or molecular level. The oligomeric molecular wires conduct voltage inputs to sensing subsystem integrated circuitry, either from an electrostatic potential arising from a targeting agent (i.e., a capture agent) binding to an intended biological or chemical target molecule, or from an electrostatic potential associated with a reference molecule that has non-specific interactions with the environment. The chirality of the oligomers imparts selectivity to either the targeting agent or the reference molecule during assembly of the sensing subsystem. |
priorityDate |
2020-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |