http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2021340170-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d33087dfb06f23a561b692aecc073feb |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-005 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7125 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-005 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7125 |
filingDate | 2021-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a5927d3d5e82f2bead26e2a3e679e7d2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_57e0ba2ae1dfde0d04859954f36e506e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f3f445509bfed0080d02b6a5fe640025 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_971f166af1c028353d6a1b09dcb81f75 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a8f575b4520bbef3be1530a861c77187 |
publicationDate | 2021-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-2021340170-A1 |
titleOfInvention | 5'-cap compounds and their uses in stabilizing rna, expressing proteins and in therapy |
abstract | The present invention relates to 5′-cap compounds, in particular the stabilization of RNA by such 5′-cap compounds, and provides compositions, such as pharmaceutical compositions, and cells comprising an RNA which is modified with such a 5′-cap compound, as well as methods for producing a peptide or protein of interest using the compositions or cells according to the present invention. Furthermore, the present invention provides the RNA, compositions, or cells for use in therapy, in particular for use in a method of treating a disease or disorder by protein replacement therapy, genome engineering, genetic reprogramming, and immunotherapy; a method for increasing the stability of RNA in cells; a method for increasing the expression of RNA in cells; and a method for providing an RNA with a 5′-cap structure. |
priorityDate | 2018-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 533.