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filingDate 2020-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_327e4519d8ba5559b26ab88f494920d9
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publicationDate 2021-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2021338420-A1
titleOfInvention Bioprosthetic valve and preparation method thereof
abstract A bioprosthetic valve and a preparation method thereof are provided. The bioprosthetic valve includes a stent and a functional biological tissue material attached to the stent. The functional biological tissue material is a biologicaltissue covalently bonded with an active group and a functional molecule or group. The method improves the anti-thrombosis and anti-calcification functions by covalently modifying the surface of a biological valve using an active group and a functional molecule or group with a substantial degree of grafting. The new bioprosthetic valve does not include aldehyde residues, exhibits excellent biocompatibility, optimal mechanical properties, high stability, and can meet the performance requirements of a biological valve delivered through a catheter.
priorityDate 2020-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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